Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28192760 | 0.97 | TAAR1 (0.50) | TAAR1ESR1PDCD1ESR2CD274 | |
| SCHEMBL169730 | 0.97 | TAAR1 (0.50) | TAAR1ESR1PDCD1ESR2CD274 | |
| SCHEMBL7499823 | 0.97 | TAAR1 (0.50) | TAAR1ESR1PDCD1ESR2CD274 | |
| SCHEMBL3900499 | 0.93 | TAAR1 (0.48) | TAAR1ESR1PDCD1ESR2CD274 | |
| Ammonia Solution, Strong SCHEMBL6989331 | 0.93 | TAAR1 (0.48) | TAAR1ESR1PDCD1ESR2CD274 | |
| Lithium SCHEMBL30443827 | 0.93 | TAAR1 (0.48) | TAAR1ESR1PDCD1ESR2CD274 | |
| Hydrogen Peroxide SCHEMBL8846644 | 0.93 | ESR1 (0.55) | TAAR1ESR1PDCD1ESR2CD274 | |
| SCHEMBL8643448 | 0.93 | ESR1 (0.55) | TAAR1ESR1PDCD1ESR2CD274 | |
| Methane SCHEMBL11277700 | 0.93 | KMT2A (0.50) | TAAR1ESR1PDCD1ESR2CD274 | |
| Ethane SCHEMBL11274743 | 0.93 | TAAR1 (0.48) | TAAR1ESR1PDCD1ESR2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969444-B2 | Flame retardant thermoplastic resin composition | CHEIL INDUSTRIES INC. (KR) | 2015-03-03 | — | — | US | claimed |
| US-20140235768-A1 | Flame Retardant Thermoplastic Resin Composition | CHEIL INDUSTRIES INC. (KR) | 2014-08-21 | — | — | US | claimed |
| CN-117203271-A | Use of a stabilizer composition for stabilizing halogen-free thermoplastic recycling material, a stabilizer composition, a masterbatch or concentrate, a stabilized plastic composition, a method for stabilizing halogen-free thermoplastic recycling material and use of a composition | 弗劳恩霍夫应用研究促进协会 | 2023-12-08 | — | — | CN | disclosed |
| CN-117015566-A | Stabilizer composition, use of a stabilizer composition, method for stabilizing polycondensates against hydrolytic degradation, and hydrolytically stable compositions and mouldings or mouldings thereof | 弗劳恩霍夫应用研究促进协会 | 2023-11-07 | — | — | CN | disclosed |
| CN-114437535-B | Flame-retardant environment-friendly polyurethane elastomer and preparation method thereof | 盛鼎高新材料有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-8969444-B2 | Flame retardant thermoplastic resin composition | CHEIL INDUSTRIES INC. (KR) | 2015-03-03 | — | — | US | disclosed |
| US-8969444-B2 | Flame retardant thermoplastic resin composition | CHEIL INDUSTRIES INC. (KR) | 2015-03-03 | — | — | US | disclosed |
| US-20140235768-A1 | Flame Retardant Thermoplastic Resin Composition | CHEIL INDUSTRIES INC. (KR) | 2014-08-21 | — | — | US | disclosed |
| US-20140235768-A1 | Flame Retardant Thermoplastic Resin Composition | CHEIL INDUSTRIES INC. (KR) | 2014-08-21 | — | — | US | disclosed |
| CN-103992571-A | Flame retardant thermoplastic resin composition | CHEIL IND INC | 2014-08-20 | — | — | CN | disclosed |
| US-8334332-B2 | Flame-retardant thermoplastic resin composition with excellent color tone | CHEIL INDUSTRIES INC. (KR) | 2012-12-18 | — | — | US | disclosed |
| US-20110160343-A1 | Flame-Retardant Thermoplastic Resin Composition with Excellent Color Tone | CHEIL INDUSTRIES INC. (KR) | 2011-06-30 | — | — | US | disclosed |
| US-6603049-B1 | Bromination process | ALBEMARLE CORPORATION | 2003-08-05 | — | — | US | disclosed |
| EP-0781262-B1 | BROMINATION PROCESS | ALBEMARLE CORP (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0790968-B1 | Process for the manufacture of decabromodiphenylethane | ALBEMARLE CORP (US) | 1999-12-08 | — | — | EP | disclosed |
| EP-0790968-A1 | IMPROVED BROMINATION PROCESS | ALBEMARLE CORPORATION (US) | 1997-08-27 | — | — | EP | disclosed |
| EP-0781262-A1 | IMPROVED BROMINATION PROCESS | ALBEMARLE CORPORATION (US) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996015087-A1 | IMPROVED BROMINATION PROCESS | ALBEMARLE CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |
| WO-1996008457-A1 | IMPROVED BROMINATION PROCESS | ALBEMARLE CORPORATION (US) | 1996-03-21 | — | — | WO | disclosed |