Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6989331

CC(c1ccccc1)c1ccccc1.N

nearest known ligand 0.55

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.48
ESR1 P03372 1/20 0.48
PDCD1 Q15116 1/20 0.48
ESR2 Q92731 1/20 0.48
CD274 Q9NZQ7 1/20 0.48
TYR P14679 1/20 0.46
ADRA2A P08913 1/20 0.46
ADRA2C P18825 1/20 0.46
CYP2D6 P10635 1/20 0.46
LMNA P02545 1/20 0.46
HIF1A Q16665 1/20 0.46
KDM4E B2RXH2 1/20 0.46
DPP4 P27487 2/20 0.45
F2 P00734 1/20 0.45
TSHR P16473 1/20 0.45
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7891727 1.00 TAAR1 (0.48) TAAR1ESR1PDCD1ESR2CD274
SCHEMBL7499823 0.97 TAAR1 (0.50) TAAR1ESR1PDCD1ESR2CD274
SCHEMBL169730 0.97 TAAR1 (0.50) TAAR1ESR1PDCD1ESR2CD274
Benzene SCHEMBL28192760 0.97 TAAR1 (0.50) TAAR1ESR1PDCD1ESR2CD274
SCHEMBL3900499 0.93 TAAR1 (0.48) TAAR1ESR1PDCD1ESR2CD274
Methane SCHEMBL11277700 0.93 KMT2A (0.50) TAAR1ESR1PDCD1ESR2CD274
Hydrogen Peroxide SCHEMBL8846644 0.93 ESR1 (0.55) TAAR1ESR1PDCD1ESR2CD274
Lithium SCHEMBL30443827 0.93 TAAR1 (0.48) TAAR1ESR1PDCD1ESR2CD274
Ethane SCHEMBL11274743 0.93 TAAR1 (0.48) TAAR1ESR1PDCD1ESR2CD274
SCHEMBL8643448 0.93 ESR1 (0.55) TAAR1ESR1PDCD1ESR2CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117089054-A Method for preparing polyurethane modified alkyd resin and preparation of high-gloss wear-resistant varnish 扬州市祥华新材料科技有限公司 2023-11-21 CN claimed
CN-116444776-A Method for preparing polyurethane modified alkyd resin and preparation of high-gloss wear-resistant varnish 扬州市祥华新材料科技有限公司 2023-07-18 CN claimed
CN-117089054-A Method for preparing polyurethane modified alkyd resin and preparation of high-gloss wear-resistant varnish 扬州市祥华新材料科技有限公司 2023-11-21 CN disclosed
CN-116444776-A Method for preparing polyurethane modified alkyd resin and preparation of high-gloss wear-resistant varnish 扬州市祥华新材料科技有限公司 2023-07-18 CN disclosed
CN-114058422-B Mannich ashless dispersant and preparation method thereof 中国石油天然气股份有限公司 2022-08-05 CN disclosed
CN-114058422-A Mannich ashless dispersant and preparation method thereof 中国石油天然气股份有限公司 2022-02-18 CN disclosed
US-6653507-B2 Useful intermediate compound of pharmaceuticals for urinary incontinence SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-11-25 US disclosed
EP-1069132-B1 Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them SERVIER LAB (FR) 2003-10-01 EP disclosed
EP-1338434-A2 Directly imageable waterless planographic printing plate precursor TORAY INDUSTRIES, INC. (JP) 2003-08-27 EP disclosed
US-6576795-B1 Racemization of optically active amines BASF AKTIENGESELLSCHAFT (DE) 2003-06-10 US disclosed
EP-1059284-B1 Racemization of optically active alkoxyamines AIR PROD & CHEM (US) 2003-05-07 EP disclosed
US-6060624-A CONTACTING THE ALKOXYISOALKYLAMINE ENANTIOMER WITH HYDROGEN AND AMMONIA IN PRESENCE OF NICKEL AND COBALT CATALYST AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-05-09 US disclosed
EP-0929534-A1 TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS Takeda Pharmaceutical Company Limited (JP) 1999-07-21 EP disclosed
EP-0923575-A1 CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS Takeda Chemical Industries, Ltd. (JP) 1999-06-23 EP disclosed
WO-1999008697-A1 TREATMENT OF CONGESTIVE HEART FAILURE WITH GROWTH HORMONE SECRETAGOGUES ELI LILLY AND COMPANY (US) 1999-02-25 WO disclosed
WO-1999008699-A1 GROWTH HORMONE SECRETAGOGUES ELI LILLY AND COMPANY (US) 1999-02-25 WO disclosed
WO-1998013356-A1 TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-04-02 WO disclosed
WO-1998008842-A1 CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-05 WO disclosed
WO-1997041846-A1 ANTI-VIRAL COMPOUNDS ELI LILLY AND COMPANY (US) 1997-11-13 WO disclosed
EP-0801083-A2 Improved functionalized resin for chemical synthesis PFIZER INC. (US) 1997-10-15 EP disclosed