Phosphine

Phosphine

SCHEMBL20163265

CCCCCCCCCCc1ccc(CCl)c(CCCCCCCCCC)c1CCCCCCCCCC.P

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.47
TP53 P04637 2/20 0.44
CYP3A4 P08684 2/20 0.44
MEN1 O00255 1/20 0.44
ALOX5 P09917 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LIPG Q9Y5X9 1/20 0.42
KCNH2 Q12809 2/20 0.40
TYMP P19971 3/20 0.39
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
ESR1 P03372 2/20 0.37
ADRA2A P08913 2/20 0.37
ADORA3 P0DMS8 2/20 0.37
TACR2 P21452 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL1535934 1.00 TYR (0.47) TYRTP53CYP3A4MEN1ALOX5
Ammonia Solution, Strong SCHEMBL20163276 0.96 TYR (0.47) TYRTP53CYP3A4MEN1ALOX5
Ammonia Solution, Strong SCHEMBL7027226 0.96 TYR (0.47) TYRTP53CYP3A4MEN1ALOX5
Ammonia Solution, Strong SCHEMBL3782696 0.96 TYR (0.47) TYRTP53CYP3A4MEN1ALOX5
Phosphine SCHEMBL6673547 0.92 CTRC (0.42) TYRTP53CYP3A4MEN1ALOX5
SCHEMBL6413165 0.90 CTRC (0.43) TYRTP53CYP3A4MEN1ALOX5
Ammonia Solution, Strong SCHEMBL995128 0.88 CTRC (0.42) TYRTP53CYP3A4MEN1ALOX5
SCHEMBL11337178 0.88 TYR (0.57) TYRTP53CYP3A4MEN1ALOX5
SCHEMBL10608218 0.88 TYR (0.57) TYRTP53CYP3A4MEN1ALOX5
SCHEMBL11331495 0.88 TYR (0.57) TYRTP53CYP3A4MEN1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10870224-B2 Method of manufacturing antireflection film FUJIFILM CORPORATION (JP) 2020-12-22 US disclosed
US-20190011604-A1 LAMINATE, METHOD OF MANUFACTURING LAMINATE, AND METHOD OF MANUFACTURING ANTIREFLECTION FILM FUJIFILM CORPORATION (JP) 2019-01-10 US disclosed
US-20180141245-A1 METHOD OF MANUFACTURING ANTIREFLECTION FILM FUJIFILM CORPORATION (JP) 2018-05-24 US disclosed