Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249383 | 0.89 | TSHR (0.38) | TSHRHPGDHTTELANEMEN1 | |
| SCHEMBL20164209 | 0.89 | TSHR (0.38) | TSHRHPGDRAB9AHTTHDAC8 | |
| SCHEMBL20164250 | 0.86 | TSHR (0.38) | TSHRHPGDRAB9AELANEMEN1 | |
| SCHEMBL20164273 | 0.82 | MAPT (0.43) | TSHRRAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL18249478 | 0.82 | TSHR (0.41) | TSHRHTTELANEMEN1ALDH1A1 | |
| SCHEMBL20164269 | 0.81 | TSHR (0.44) | TSHRHTTHDAC8ELANEALDH1A1 | |
| SCHEMBL18249379 | 0.81 | KMT2A (0.39) | TSHRRAB9AHDAC8MEN1ALDH1A1 | |
| SCHEMBL20164300 | 0.80 | ABCB1 (0.38) | TSHRRAB9AHDAC8ALDH1A1KMT2A | |
| SCHEMBL18249457 | 0.78 | LMNA (0.41) | HPGDRAB9AELANEALDH1A1KMT2A | |
| SCHEMBL19899256 | 0.78 | TSHR (0.45) | TSHRHPGDRAB9AHTTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |