SCHEMBL20165424

SCHEMBL20165424

C/C=C/c1ccc(Oc2cc(/C=C/C)ccc2OC)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.64
TUBB P07437 1/20 0.64
TUBA3C P0DPH7 1/20 0.64
TUBA1B P68363 1/20 0.64
TUBA4A P68366 1/20 0.64
TUBB4B P68371 1/20 0.64
TUBB3 Q13509 1/20 0.64
TUBB2A Q13885 1/20 0.64
TUBB8 Q3ZCM7 1/20 0.64
TUBA3E Q6PEY2 1/20 0.64
TUBA1A Q71U36 1/20 0.64
TUBA1C Q9BQE3 1/20 0.64
TUBB6 Q9BUF5 1/20 0.64
TUBB2B Q9BVA1 1/20 0.64
TUBB1 Q9H4B7 1/20 0.64
ALDH1A1 P00352 4/20 0.58
LMNA P02545 3/20 0.58
TP53 P04637 1/20 0.58
CYP3A4 P08684 1/20 0.58
TSHR P16473 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylisoeugenol SCHEMBL1532669 0.85 TYR (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Methylisoeugenol SCHEMBL29518298 0.85 TYR (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Methylisoeugenol SCHEMBL29364555 0.85 TYR (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Methylisoeugenol SCHEMBL1760676 0.85 TYR (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Methylisoeugenol SCHEMBL112937 0.85 TYR (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Methylisoeugenol SCHEMBL30203196 0.85 TYR (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Methylisoeugenol SCHEMBL28577260 0.83 TYR (0.67) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Methylisoeugenol SCHEMBL28544349 0.83 TYR (0.67) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL17627677 0.83 TTR (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL27943686 0.82 TYR (0.65) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109982993-B Asymmetrically substituted dienyl diphenyl ethers, their preparation and use 赢创运营有限公司 2022-06-07 CN claimed
EP-3541773-B1 ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE EVONIK OPERATIONS GMBH (DE) 2020-05-13 EP claimed
US-20190367652-A1 ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE EVONIK TECHNOCHEMIE GMBH (DE) 2019-12-05 US claimed
EP-3541773-A1 ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE Evonik Technochemie GmbH (DE) 2019-09-25 EP claimed
WO-2018091253-A1 ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE EVONIK TECHNOCHEMIE GMBH (DE) 2018-05-24 WO claimed
CN-109982993-B Asymmetrically substituted dienyl diphenyl ethers, their preparation and use 赢创运营有限公司 2022-06-07 CN disclosed
EP-3541773-B1 ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE EVONIK OPERATIONS GMBH (DE) 2020-05-13 EP disclosed
US-20190367652-A1 ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE EVONIK TECHNOCHEMIE GMBH (DE) 2019-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190367652-A1 ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE ITGB3, C9, CBR3 TUBB4A 837/4885TUBB 1149/4885TUBA3C 822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.