Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 11/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087947 | 0.88 | CA12 (0.46) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL20165514 | 0.86 | ALDH1A1 (0.52) | ALDH1A1ALDH2KDM5AKDM4CFFAR3 | |
| Hydrochloric Acid SCHEMBL28190002 | 0.86 | CA12 (0.44) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL20165511 | 0.81 | AKR1B1 (0.47) | ALDH1A1KDM5AKDM4CCA12CA9 | |
| SCHEMBL20165471 | 0.80 | KDM4C (0.41) | ALDH1A1ALDH2KDM5AKDM4CCA12 | |
| SCHEMBL13638256 | 0.80 | CA12 (0.47) | ALDH1A1ALDH2HPGDCA12CA2 | |
| SCHEMBL5696536 | 0.80 | CA12 (0.40) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL11419403 | 0.79 | CA12 (0.43) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL8084070 | 0.79 | ALDH1A1 (0.45) | ALDH1A1ALDH2HPGDKDM5AKDM4C | |
| SCHEMBL17987028 | 0.78 | CA14 (0.45) | ALDH1A1ALDH2HPGDKDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541857-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018091375-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | WO | disclosed |