Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | RXRA | P19793 | 5/20 | 0.37 |
| ▸ | RARA | P10276 | 4/20 | 0.37 |
| ▸ | RARB | P10826 | 4/20 | 0.37 |
| ▸ | RARG | P13631 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | SNCA | P37840 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384777 | 0.76 | TRPV1 (0.33) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL9095950 | 0.69 | ALDH1A1 (0.57) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL13447729 | 0.67 | ALDH1A1 (0.56) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL9414657 | 0.66 | — | — | |
| SCHEMBL11424674 | 0.66 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP3A4MAPK1APP | |
| SCHEMBL11424673 | 0.66 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP3A4MAPK1APP | |
| SCHEMBL10799157 | 0.66 | ALDH1A1 (0.70) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL2842101 | 0.66 | TRPV1 (0.31) | TRPV1 | |
| SCHEMBL11782744 | 0.66 | CA1 (0.33) | CYP3A4LMNAKMT2ATP53 | |
| SCHEMBL11782471 | 0.66 | CA1 (0.33) | CYP3A4LMNAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541783-A1 | PRECURSOR COMPOUNDS FOR PROVIDING RETINOIDS OF THE VITAMIN A5 PATHWAY AND USES THEREOF | University of Debrecen (HU) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018091937-A1 | PRECURSOR COMPOUNDS FOR PROVIDING RETINOIDS OF THE VITAMIN A5 PATHWAY AND USES THEREOF | UNIVERSITY OF DEBRECEN (HU) | 2018-05-24 | — | — | WO | disclosed |