Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20166112 | 1.00 | RIPK1 (0.65) | RIPK1 | |
| SCHEMBL20168839 | 0.89 | RIPK1 (0.70) | RIPK1 | |
| SCHEMBL20168843 | 0.89 | RIPK1 (0.70) | RIPK1 | |
| SCHEMBL20166533 | 0.83 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL20166200 | 0.83 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL20166197 | 0.83 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL20166531 | 0.83 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL20165943 | 0.82 | RIPK1 (0.68) | RIPK1 | |
| SCHEMBL20165818 | 0.82 | RIPK1 (0.68) | RIPK1 | |
| SCHEMBL20165946 | 0.82 | RIPK1 (0.68) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541813-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018092089-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-05-24 | — | — | WO | disclosed |