Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 7/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20166910 | 0.89 | KDM4E (0.39) | ALOX5ALDH1A1KDM4EPPARGPPARD | |
| SCHEMBL20137060 | 0.87 | MGLL (0.41) | ALOX5ALDH1A1KDM4EPPARGPPARD | |
| SCHEMBL20137009 | 0.84 | MGLL (0.36) | ALOX5ALDH1A1KDM4EPPARGPPARD | |
| SCHEMBL20137037 | 0.84 | KDM4E (0.38) | ALDH1A1KDM4EPPARGPPARDPPARA | |
| SCHEMBL20137115 | 0.83 | LTB4R2 (0.44) | PPARGDHFRCETP | |
| Hydrochloric Acid SCHEMBL20137043 | 0.83 | KDM4E (0.37) | ALDH1A1KDM4EPPARGPPARDPPARA | |
| SCHEMBL20137089 | 0.82 | FFAR4 (0.39) | ALDH1A1KDM4EPPARGPPARDPPARA | |
| SCHEMBL29561187 | 0.82 | FFAR4 (0.39) | ALDH1A1KDM4EPPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL20137048 | 0.81 | FFAR4 (0.39) | ALDH1A1KDM4EPPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL29560707 | 0.81 | FFAR4 (0.39) | ALDH1A1KDM4EPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |