Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 3/20 | 0.37 |
| ▸ | PRKACG | P22612 | 2/20 | 0.37 |
| ▸ | PRKACB | P22694 | 2/20 | 0.37 |
| ▸ | PRKCB | P05771 | 13/20 | 0.37 |
| ▸ | PRKCA | P17252 | 12/20 | 0.37 |
| ▸ | GSK3B | P49841 | 12/20 | 0.37 |
| ▸ | PRKCG | P05129 | 11/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 7/20 | 0.37 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 2/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1993567 | 0.90 | CAMK2D (0.41) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL1990076 | 0.89 | CAMK2D (0.48) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL1993512 | 0.89 | CAMK2D (0.44) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL1991673 | 0.88 | CAMK2D (0.40) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL1993579 | 0.85 | PRKACA (0.49) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL1990843 | 0.85 | CAMK2D (0.44) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL1992218 | 0.82 | CAMK2D (0.49) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL1996421 | 0.82 | CAMK2D (0.50) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL1991812 | 0.82 | CAMK2D (0.45) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL12563848 | 0.81 | CAMK2D (0.45) | CAMK2DPRKACAPRKACGPRKACBPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |