Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20137034 | 0.90 | MGLL (0.62) | MGLLALDH1A1POLBKDM4E | |
| SCHEMBL20168721 | 0.88 | MGLL (0.54) | MGLLALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL20137106 | 0.80 | MGLL (0.75) | MGLL | |
| SCHEMBL29561175 | 0.80 | MGLL (0.75) | MGLL | |
| SCHEMBL20151763 | 0.78 | MGLL (0.84) | MGLL | |
| SCHEMBL20137015 | 0.78 | MGLL (0.69) | MGLL | |
| SCHEMBL20136968 | 0.78 | MGLL (0.53) | MGLLALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL20136931 | 0.77 | MGLL (1.00) | MGLL | |
| SCHEMBL20168789 | 0.75 | MGLL (0.62) | MGLLALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL20158332 | 0.70 | MGLL (0.79) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |