Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 18/20 | 0.78 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20136967 | 0.88 | MGLL (1.00) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20137387 | 0.81 | MGLL (0.67) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20151802 | 0.78 | MGLL (0.83) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20137047 | 0.78 | MGLL (0.50) | MGLLABHD6CYP2D6PLA2G7MEN1 | |
| SCHEMBL20137045 | 0.78 | MGLL (0.50) | MGLLABHD6CYP2D6PLA2G7MEN1 | |
| SCHEMBL20137122 | 0.77 | MGLL (1.00) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20151756 | 0.77 | MGLL (0.71) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20137393 | 0.77 | MGLL (0.80) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL29509676 | 0.77 | MGLL (0.80) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20137028 | 0.77 | MGLL (1.00) | MGLLABHD6CYP2D6PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |