Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320190 | 0.78 | TRPV1 (0.50) | KMT2AMEN1LMNA | |
| SCHEMBL9250363 | 0.77 | POLB (0.48) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL7378487 | 0.77 | HTR2A (0.50) | ALDH1A1KMT2AMEN1MAPTHTR2A | |
| SCHEMBL5275044 | 0.77 | HTR2A (0.76) | KMT2AMEN1HTR2AHTR2CHTR2B | |
| SCHEMBL7431362 | 0.77 | MAPT (0.63) | ALDH1A1KMT2AMEN1MAPTHTR2A | |
| SCHEMBL8113403 | 0.76 | ATM (0.57) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL22274969 | 0.74 | KMT2A (0.52) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL28853057 | 0.74 | TRPV1 (0.54) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL2930056 | 0.73 | HTR2A (0.59) | KMT2AMEN1MAPTHTR2AHTR2C | |
| SCHEMBL2979188 | 0.73 | KMT2A (0.57) | ALDH1A1KMT2AMEN1MAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11931329-B2 | Compositions and methods for treating anxiety-related disorders | YAMO PHARMACEUTICALS LLC (US) | 2024-03-19 | — | — | US | claimed |
| EP-3541411-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | Tyme, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093820-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | TYME, INC. (US) | 2018-05-24 | — | — | WO | disclosed |