Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940302 | 0.87 | KMT2A (0.59) | ATMKDM4EKMT2AMEN1CA12 | |
| SCHEMBL1032004 | 0.85 | KDM4E (0.62) | ATMKDM4ECYP19A1KMT2AMEN1 | |
| SCHEMBL28176844 | 0.85 | KDM4E (0.62) | ATMKDM4ECYP19A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10448977 | 0.83 | KDM4E (0.61) | ATMKDM4ECYP19A1KMT2AMEN1 | |
| SCHEMBL3579994 | 0.83 | ALOX5 (0.66) | ATMKDM4EKMT2AMEN1CA12 | |
| SCHEMBL491276 | 0.83 | CYP4F2 (0.59) | ATMKDM4EKMT2AMEN1CA12 | |
| SCHEMBL347209 | 0.81 | FFAR4 (0.61) | ATMKDM4EKMT2AMEN1CA12 | |
| SCHEMBL269005 | 0.81 | NPC1 (0.61) | ATMKDM4ECYP19A1KMT2AMEN1 | |
| SCHEMBL22345345 | 0.81 | ALOX5 (0.56) | KMT2AMEN1ALDH1A1ALOX5LTA4H | |
| SCHEMBL29641938 | 0.80 | ALOX5 (0.54) | KMT2AMEN1ALDH1A1ALOX5LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004581-A2 | Process for the preparation of thalidomide | CELGENE CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |