Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Lactic Acid SCHEMBL31379959 | 1.00 | TSHR (0.58) | TSHRALDH1A1TP53FGFR4LMNA | |
| Acrylamide SCHEMBL9851808 | 0.86 | TSHR (0.61) | TSHRALDH1A1TP53FGFR4LMNA | |
| Acrylamide SCHEMBL11326871 | 0.86 | — | — | |
| Acrylamide SCHEMBL27396969 | 0.86 | — | — | |
| Alanine SCHEMBL9851813 | 0.84 | TSHR (0.58) | TSHRALDH1A1TP53FGFR4LMNA | |
| Alanine SCHEMBL28538271 | 0.84 | TSHR (0.58) | TSHRALDH1A1TP53FGFR4LMNA | |
| D-Alanine SCHEMBL30582491 | 0.84 | TSHR (0.58) | TSHRALDH1A1TP53FGFR4LMNA | |
| Lactic Acid SCHEMBL18398168 | 0.83 | TP53 (0.65) | TSHRALDH1A1TP53FGFR4LMNA | |
| Lactic Acid SCHEMBL453357 | 0.83 | TP53 (0.65) | TSHRALDH1A1TP53FGFR4LMNA | |
| L-Lactic Acid SCHEMBL29395214 | 0.83 | TP53 (0.65) | TSHRALDH1A1TP53FGFR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117981518-A | Device, method and application for improving planting soil | 国能神东煤炭集团有限责任公司 | 2024-05-07 | — | — | CN | claimed |
| CN-109689798-A | Method for producing water-soluble thermally crosslinkable polymer materials | 诺华股份有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109629242-A | A kind of manufacturing method of spunlace non-woven fabric wall paper | 杭州尊尚壁装饰材料有限公司 | 2019-04-16 | — | — | CN | claimed |
| WO-2018092151-A1 | PROCESS FOR THE PREPARATION OF 2-(E)-N-HYDROXY-3-[4-[[[2-(2-METHYL-1H-INDOL-3-YL) ETHYL]AMINO]METHYL]PHENYL]-2-PROPENAMIDE 2-HYDROXYPROPANOIC ACID (1:1) AND ITS POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2018-05-24 | — | — | WO | claimed |
| CN-118063805-A | Polylactic acid-based high-strength antibacterial hydrogel and preparation method thereof | 南京大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-117981518-A | Device, method and application for improving planting soil | 国能神东煤炭集团有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-109690360-A | Method for producing the haptic lens with durable lubricant coating on it | 诺华股份有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109689798-A | Method for producing water-soluble thermally crosslinkable polymer materials | 诺华股份有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109629242-A | A kind of manufacturing method of spunlace non-woven fabric wall paper | 杭州尊尚壁装饰材料有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-202702761-U | Medical film | HANGZHOU KONIDA MEDICAL INSTR FACTORY | 2013-01-30 | — | — | CN | disclosed |