Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL18398168 | 1.00 | TP53 (0.65) | TP53LMNATSHRALDH1A1ALOX15 | |
| L-Lactic Acid SCHEMBL29395214 | 1.00 | TP53 (0.65) | TP53LMNATSHRALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL8311226 | 0.88 | — | — | |
| Acrylic Acid SCHEMBL29930950 | 0.88 | LMNA (0.67) | TP53LMNATSHRALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL3647787 | 0.88 | — | — | |
| Acrylic Acid SCHEMBL731674 | 0.88 | LMNA (0.67) | TP53LMNATSHRALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL2727798 | 0.88 | LMNA (0.67) | TP53LMNATSHRALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL1775547 | 0.85 | LMNA (0.62) | TP53LMNATSHRALDH1A1ALOX15 | |
| Lactic Acid SCHEMBL16555873 | 0.85 | TP53 (0.69) | TP53LMNATSHRALDH1A1 | |
| Acrylic Acid SCHEMBL11573171 | 0.85 | LMNA (0.62) | TP53LMNATSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494289-A | The method of inkjet printing on rectifier | ALIGN TECHNOLOGY INC | 2019-11-22 | — | — | CN | claimed |
| CN-105820050-B | A kind of environment-friendly type lactate acrylate monomer and preparation method thereof | 苏州吉人高新材料股份有限公司 | 2018-11-02 | — | — | CN | claimed |
| CN-107693506-A | Magnetic lignin nano-medicament carrier | 天津科技大学 | 2018-02-16 | — | — | CN | claimed |
| US-9650651-B2 | Method for production of n-propanol and other C3-containing products from syngas by symbiotic co-cultures of anaerobic microorganisms | SYNATA BIO, INC. | 2017-05-16 | — | — | US | claimed |
| CN-105646202-A | Preparation method of UV monomer for paint and UV monomer for paint | 苏州吉人高新材料股份有限公司 | 2016-06-08 | — | — | CN | claimed |
| WO-2014140335-A1 | METHOD FOR PRODUCTION OF N-PROPANOL AND OTHER C3-CONTAINING PRODUCTS FROM SYNGAS BY SYMBIOTIC CO-CULTURES OF ANAEROBIC MICROORGANISMS | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2014-09-18 | — | — | WO | claimed |
| US-20140273120-A1 | Method for production of n-propanol and other C3-containing products from syngas by symbiotic co-cultures of anaerobic microorganisms | SYNATA BIO, INC. | 2014-09-18 | — | — | US | claimed |
| EP-1077677-B1 | PROCESS FOR THE MANUFACTURE OF A BIOLOGICALLY ACTIVE COMPOSITION | JAGOTEC AG (CH) | 2003-10-22 | — | — | EP | claimed |
| WO-2002068527-A2 | NOVEL β-OXO COMPOUNDS AND THEIR USE IN PHOTORESIST | ARCH SPECIALTY CHEMICALS, INC. (US) | 2002-09-06 | — | — | WO | claimed |
| EP-1077677-A1 | BIOLOGICALLY ACTIVE COMPOSITION | BIOGLAN AB (SE) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058109-A1 | BIOLOGICALLY ACTIVE COMPOSITION | BIOGLAN AB (SE) | 1999-11-18 | — | — | WO | claimed |
| CN-107848939-B | Method for producing acrylic acid with acetaldehyde as main by-product | PTT全球化学公众有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-110105190-A | Method for producing acrylic acid based on lactic acid aqueous solution of ester | 清华大学 | 2019-08-09 | — | — | CN | disclosed |
| CN-109937462-A | Light-driven ion pump film feeding system | 加州大学董事会 | 2019-06-25 | — | — | CN | disclosed |
| CN-109689876-A | Method for producing alcohols under aerobic conditions and for extracting products using oleyl alcohol | 赢创德固赛有限公司 | 2019-04-26 | — | — | CN | disclosed |
| US-6201065-B1 | BLOCK POLYMERS AND MACROMONOMERS | FOCAL, INC. | 2001-03-13 | — | — | US | disclosed |
| EP-1077677-A1 | BIOLOGICALLY ACTIVE COMPOSITION | BIOGLAN AB (SE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058109-A1 | BIOLOGICALLY ACTIVE COMPOSITION | BIOGLAN AB (SE) | 1999-11-18 | — | — | WO | disclosed |
| EP-0842209-A2 | MULTIBLOCK BIODEGRADABLE HYDROGELS FOR USE AS CONTROLLED RELEASE AGENTS FOR DRUGS AND TISSUE TREATMENT AGENTS | FOCAL, INC. (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005185-A2 | MULTIBLOCK BIODEGRADABLE HYDROGELS FOR USE AS CONTROLLED RELEASE AGENTS FOR DRUGS DELIVERY AND TISSUE TREATMENT AGENTS | FOCAL, INC. (US) | 1997-02-13 | — | — | WO | disclosed |