SCHEMBL20168856

SCHEMBL20168856

CC[C@H](O)C1(C(=O)O)CC1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4553549 1.00 FFAR3 (0.35) FFAR3
SCHEMBL164042 1.00 FFAR3 (0.35) FFAR3
SCHEMBL9935954 0.91 CYP2C19 (0.34) FFAR3
SCHEMBL14037320 0.91 CYP2C19 (0.34) FFAR3
SCHEMBL17507162 0.89 CYP2C19 (0.38) FFAR3
SCHEMBL21085003 0.86
SCHEMBL15201851 0.84 KCNA3 (0.32)
SCHEMBL10521828 0.76 FFAR3 (0.35) FFAR3
SCHEMBL17099453 0.76 GPR84 (0.50)
SCHEMBL23114077 0.74 FFAR3 (0.33) FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347575-A1 BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS Albireo AB (SE) 2024-04-10 EP disclosed
WO-2022253997-A1 BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS ALBIREO AB (SE) 2022-12-08 WO disclosed
EP-3793994-A1 INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE Biogen MA Inc. (US) 2021-03-24 EP disclosed
EP-3704097-A1 BICYCLIC SULFONES AND SULFOXIDES AND METHODS OF USE THEREOF F. Hoffmann-La Roche AG (CH) 2020-09-09 EP disclosed
EP-3541820-A1 MAGL INHIBITORS Abide Therapeutics, Inc. (US) 2019-09-25 EP disclosed
EP-3541821-A1 MAGL INHIBITORS Abide Therapeutics, Inc. (US) 2019-09-25 EP disclosed
WO-2018093947-A1 MAGL INHIBITORS ABIDE THERAPEUTICS, INC. (US) 2018-05-24 WO disclosed
WO-2018093949-A1 MAGL INHIBITORS ABIDE THERAPEUTICS, INC. (US) 2018-05-24 WO disclosed