Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28684969 | 0.84 | HSD17B10 (0.38) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL20165470 | 0.82 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL28694775 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL13321723 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL24661795 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL28702852 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL20165510 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL28482602 | 0.77 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL28870483 | 0.77 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL28870482 | 0.77 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541857-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018091375-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | WO | disclosed |