Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17827190 | 1.00 | KDM4E (0.37) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL22258108 | 0.96 | KDM4E (0.35) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15087892 | 0.95 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL17929454 | 0.92 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL24936770 | 0.91 | HSP90AA1 (0.34) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL20706873 | 0.91 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL20821686 | 0.90 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL17827188 | 0.90 | ALDH1A1 (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL20706817 | 0.90 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL20633754 | 0.90 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9978946-B2 | Spirobifluorene compound for light emitting devices | SUMITOMO CHEMICAL CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |
| US-9978946-B2 | Spirobifluorene compound for light emitting devices | SUMITOMO CHEMICAL CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |