Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15087889 | 1.00 | ATM (0.39) | ATML3MBTL1KDM4EPDK2HDAC4 | |
| SCHEMBL20411906 | 0.92 | KDM4E (0.39) | ATML3MBTL1KDM4EPDK2HDAC4 | |
| SCHEMBL17854693 | 0.91 | ATM (0.40) | ATML3MBTL1KDM4EPDK2HDAC4 | |
| SCHEMBL14595493 | 0.90 | PDK2 (0.41) | ATML3MBTL1KDM4EPDK2HDAC4 | |
| SCHEMBL18160230 | 0.89 | L3MBTL1 (0.43) | ATML3MBTL1KDM4EPDK2HDAC4 | |
| SCHEMBL17854688 | 0.88 | KDM4E (0.40) | ATML3MBTL1KDM4EPDK2HDAC4 | |
| SCHEMBL21138923 | 0.88 | KDM4E (0.39) | ATML3MBTL1KDM4EPDK2HDAC4 | |
| SCHEMBL15213619 | 0.88 | PDK2 (0.38) | ATML3MBTL1KDM4EPDK2MEN1 | |
| SCHEMBL27016268 | 0.88 | KDM4E (0.42) | ATML3MBTL1KDM4EPDK2MEN1 | |
| SCHEMBL22928199 | 0.88 | KDM4E (0.46) | ATML3MBTL1KDM4EPDK2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9978946-B2 | Spirobifluorene compound for light emitting devices | SUMITOMO CHEMICAL CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |
| US-9978946-B2 | Spirobifluorene compound for light emitting devices | SUMITOMO CHEMICAL CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |