SCHEMBL20169332

SCHEMBL20169332

Cc1cc(-c2ccc(-c3nc(C(F)(F)F)cn3COCCS(C)(C)C)cn2)ccc1OCC(C)(C)C(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 16/20 0.45
AAK1 Q2M2I8 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15282817 0.90 DGAT1 (0.56) DGAT1AAK1
SCHEMBL20169343 0.83 DGAT1 (0.53) DGAT1
SCHEMBL20169336 0.83 DGAT1 (0.63) DGAT1
SCHEMBL20169337 0.82 DGAT1 (0.51) DGAT1
SCHEMBL20169312 0.80 DGAT1 (0.53) DGAT1
SCHEMBL20169313 0.79 DGAT1 (0.54) DGAT1
SCHEMBL20169316 0.79 DGAT1 (0.46) DGAT1
SCHEMBL20169376 0.78 DGAT1 (0.51) DGAT1
SCHEMBL20169311 0.77 DGAT1 (0.48) DGAT1
SCHEMBL10176798 0.77 DGAT1 (0.60) DGAT1AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9975871-B2 Continuous arycyclic compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2018-05-22 US disclosed