Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15282957 | 0.89 | DGAT1 (0.65) | DGAT1PTGER4ALKBH1GRM5CASP3 | |
| SCHEMBL20169386 | 0.89 | DGAT1 (0.54) | DGAT1PTGER4ALKBH1GRM5CASP3 | |
| SCHEMBL20169341 | 0.85 | DGAT1 (0.55) | DGAT1PTGER4ALKBH1GRM5CASP3 | |
| SCHEMBL9935301 | 0.78 | DGAT1 (0.68) | DGAT1PTGER4ALKBH1CASP3SENP8 | |
| SCHEMBL20169329 | 0.76 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL9936494 | 0.74 | DGAT1 (0.69) | DGAT1PTGER4ALKBH1GRM5CASP3 | |
| SCHEMBL18541097 | 0.72 | DGAT1 (0.82) | DGAT1PTGER4ALKBH1CASP3SENP8 | |
| SCHEMBL16787744 | 0.71 | DGAT1 (0.66) | DGAT1PTGER4ALKBH1GRM5CASP3 | |
| SCHEMBL20169313 | 0.71 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL16787677 | 0.70 | DGAT1 (0.73) | DGAT1PTGER4GRM5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975871-B2 | Continuous arycyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |