Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 12/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15282959 | 0.87 | DGAT1 (0.51) | DGAT1NPC1MAPTSTAT3RAB9A | |
| SCHEMBL20169313 | 0.82 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL20169341 | 0.75 | DGAT1 (0.55) | DGAT1MTOR | |
| SCHEMBL16661047 | 0.75 | DGAT1 (0.54) | DGAT1KDM1ANPC1MAPTSTAT3 | |
| SCHEMBL20169312 | 0.74 | DGAT1 (0.53) | DGAT1 | |
| SCHEMBL16660872 | 0.73 | DGAT1 (0.52) | DGAT1NPC1MAPTSTAT3RAB9A | |
| SCHEMBL20169384 | 0.72 | DGAT1 (0.49) | DGAT1MAPTATM | |
| SCHEMBL16787678 | 0.70 | DGAT1 (0.62) | DGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20169329 | 0.70 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL20428497 | 0.69 | DGAT1 (0.60) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975871-B2 | Continuous arycyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |