Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169356 | 0.92 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL15282917 | 0.90 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL20169336 | 0.84 | DGAT1 (0.63) | DGAT1 | |
| SCHEMBL18085597 | 0.83 | DGAT1 (0.59) | DGAT1 | |
| SCHEMBL20169350 | 0.82 | DGAT1 (0.53) | DGAT1 | |
| SCHEMBL15282776 | 0.82 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL17772415 | 0.81 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL20169313 | 0.81 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL20169346 | 0.80 | DGAT1 (0.52) | DGAT1 | |
| SCHEMBL20169312 | 0.80 | DGAT1 (0.53) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975871-B2 | Continuous arycyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |