Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21683000 | 0.88 | CYP19A1 (0.60) | CYP3A4MAPTCYP2C19ALDH1A1HPGD | |
| SCHEMBL30343625 | 0.88 | MAPT (0.57) | CYP3A4MAPTCYP2C19ALDH1A1HPGD | |
| SCHEMBL15668252 | 0.88 | MAPT (0.57) | CYP3A4MAPTCYP2C19ALDH1A1HPGD | |
| SCHEMBL30343628 | 0.86 | CYP3A4 (0.55) | CYP3A4MAPTCYP2C19ALDH1A1HPGD | |
| SCHEMBL30343633 | 0.86 | CYP3A4 (0.55) | CYP3A4MAPTCYP2C19ALDH1A1HPGD | |
| SCHEMBL15668031 | 0.86 | CYP3A4 (0.55) | CYP3A4MAPTCYP2C19ALDH1A1HPGD | |
| SCHEMBL19505611 | 0.86 | CYP3A4 (0.52) | CYP3A4MAPTCYP2C19ALDH1A1HPGD | |
| SCHEMBL15668055 | 0.84 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C19ALDH1A1HPGD | |
| SCHEMBL30233473 | 0.82 | MAPT (0.60) | CYP3A4MAPTCYP2C19ALDH1A1HPGD | |
| SCHEMBL6617327 | 0.82 | MAPT (0.60) | CYP3A4MAPTCYP2C19ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975868-B2 | 7,8-dihydoxyflavone and 7,8-substituted flavone derivatives, compositions, and methods related thereto | EMORY UNIVERSITY (US) | 2018-05-22 | — | — | US | disclosed |