Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | TERT | O14746 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | IKBKB | O14920 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21683039 | 0.92 | CYP19A1 (0.58) | CYP19A1MAPTHPGDCYP3A4TERT | |
| SCHEMBL20169560 | 0.88 | CYP3A4 (0.54) | CYP19A1MAPTHPGDCYP3A4TERT | |
| SCHEMBL21683005 | 0.88 | MAPT (0.60) | CYP19A1MAPTHPGDCYP3A4TERT | |
| SCHEMBL21682943 | 0.87 | CYP19A1 (0.67) | CYP19A1MAPTHPGDCYP3A4TERT | |
| SCHEMBL21682940 | 0.87 | CYP19A1 (0.67) | CYP19A1MAPTHPGDCYP3A4TERT | |
| SCHEMBL21682931 | 0.85 | MAPT (0.56) | CYP19A1MAPTHPGDCYP3A4TERT | |
| SCHEMBL21683060 | 0.85 | MAPT (0.56) | CYP19A1MAPTHPGDCYP3A4TERT | |
| SCHEMBL6615809 | 0.84 | MAPT (0.64) | CYP19A1MAPTHPGDCYP3A4TERT | |
| SCHEMBL21682939 | 0.81 | MAPT (0.60) | CYP19A1MAPTHPGDCYP3A4TERT | |
| SCHEMBL21682923 | 0.81 | MAPT (0.60) | CYP19A1MAPTHPGDCYP3A4TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033960-A1 | Substituted Dihydroxyflavone Derivatives, Compositions, and Methods Related Thereto | EMORY UNIVERSITY (US) | 2020-02-13 | — | — | WO | disclosed |