Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22020057 | 0.83 | CA1 (0.47) | DPP7DPP8LMNAMAPTMAPK1 | |
| SCHEMBL7598854 | 0.82 | DPP4 (0.41) | DPP7DPP4DPP8DPP9LMNA | |
| SCHEMBL15472444 | 0.82 | CNR1 (0.43) | LMNAMAPTMAPK1CNR1CA1 | |
| SCHEMBL20169776 | 0.80 | GNAI3 (0.65) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL20169781 | 0.80 | GNAI3 (0.65) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL20169779 | 0.80 | GNAI3 (0.65) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL14042153 | 0.80 | GNAI3 (0.40) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL12257904 | 0.80 | GNAI3 (0.60) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL23073481 | 0.79 | GNAI3 (0.55) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL14627818 | 0.79 | DPP7 (0.56) | GNAI3GNAO1GNAI1DPP7RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975847-B2 | Amino acid derivatives and their uses | JOHNSON & JOHNSON CONSUMER INC. (US) | 2018-05-22 | — | — | US | disclosed |