Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523246 | 0.92 | PDE4A (0.48) | SLC5A1SLC5A2HDAC8PDE4APDE4B | |
| SCHEMBL30141127 | 0.85 | SLC5A1 (0.55) | SLC5A1SLC5A2HDAC8PDE4APDE4B | |
| SCHEMBL30892461 | 0.85 | SLC5A1 (0.55) | SLC5A1SLC5A2HDAC8PDE4APDE4B | |
| SCHEMBL24983808 | 0.85 | SLC5A1 (0.55) | SLC5A1SLC5A2HDAC8PDE4APDE4B | |
| SCHEMBL29179272 | 0.85 | SLC5A1 (0.55) | SLC5A1SLC5A2HDAC8PDE4APDE4B | |
| SCHEMBL4414040 | 0.83 | SLC5A1 (0.63) | SLC5A1SLC5A2PDE4APDE4BPDE4C | |
| SCHEMBL13117246 | 0.83 | SLC5A1 (0.63) | SLC5A1SLC5A2PDE4APDE4BPDE4C | |
| SCHEMBL30141030 | 0.82 | SLC5A1 (0.52) | SLC5A1SLC5A2HDAC8PDE4APDE4B | |
| SCHEMBL24983672 | 0.82 | SLC5A1 (0.52) | SLC5A1SLC5A2HDAC8PDE4APDE4B | |
| SCHEMBL30892451 | 0.82 | SLC5A1 (0.52) | SLC5A1SLC5A2HDAC8PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981260-B1 | NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS | SPHAERA PHARMA PRIVATE LTD (IN) | 2021-01-13 | — | — | EP | disclosed |
| US-9975869-B2 | Analogues of epicatechin and related polyphenols | SPHAERA PHARMA PVT. LTD. (IN) | 2018-05-22 | — | — | US | disclosed |