Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | APEX1 | P27695 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | SNCA | P37840 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | ALPL | P05186 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.68 |
| ▸ | RAD52 | P43351 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169845 | 1.00 | BACE1 (0.68) | BACE1KDM4EPTGS1GAAMEN1 | |
| SCHEMBL14701451 | 0.93 | BACE1 (0.65) | BACE1KDM4EPTGS1GAAMEN1 | |
| SCHEMBL29682334 | 0.93 | BACE1 (0.65) | BACE1KDM4EPTGS1GAAMEN1 | |
| SCHEMBL29105259 | 0.93 | BACE1 (0.65) | BACE1KDM4EPTGS1GAAMEN1 | |
| SCHEMBL348595 | 0.88 | BACE1 (0.74) | BACE1KDM4EPTGS1GAAMEN1 | |
| SCHEMBL29934352 | 0.88 | BACE1 (0.74) | BACE1KDM4EPTGS1GAAMEN1 | |
| SCHEMBL30843342 | 0.88 | BACE1 (0.74) | BACE1KDM4EPTGS1GAAMEN1 | |
| SCHEMBL348596 | 0.88 | BACE1 (0.74) | BACE1KDM4EPTGS1GAAMEN1 | |
| SCHEMBL349872 | 0.88 | BACE1 (0.74) | BACE1KDM4EPTGS1GAAMEN1 | |
| SCHEMBL5333406 | 0.88 | BACE1 (0.70) | BACE1KDM4EPTGS1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233810-B | Preparation method and application of hydroxycinnamoyl ester type catechin | 安徽农业大学 | 2023-03-21 | — | — | CN | claimed |
| CN-111233810-A | Preparation method and application of hydroxycinnamoyl ester type catechin | 安徽农业大学 | 2020-06-05 | — | — | CN | claimed |
| CN-111233810-B | Preparation method and application of hydroxycinnamoyl ester type catechin | 安徽农业大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-111233810-A | Preparation method and application of hydroxycinnamoyl ester type catechin | 安徽农业大学 | 2020-06-05 | — | — | CN | disclosed |
| US-9975869-B2 | Analogues of epicatechin and related polyphenols | SPHAERA PHARMA PVT. LTD. (IN) | 2018-05-22 | — | — | US | disclosed |