SCHEMBL20170560

SCHEMBL20170560

CC(C)COC(C)[C@H](N)C(=O)OCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 3/20 0.48
SLC1A3 P43003 2/20 0.48
SLC1A2 P43004 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
ALDH1A1 P00352 4/20 0.47
SLC15A1 P46059 1/20 0.47
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LTA4H P09960 1/20 0.42
LAP3 P28838 1/20 0.42
TSHR P16473 1/20 0.41
CTSK P43235 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5196443 0.89 SLC1A3 (0.55) SLC1A1SLC1A3SLC1A2KMT2AMEN1
SCHEMBL19853299 0.89 SLC1A3 (0.55) SLC1A1SLC1A3SLC1A2KMT2AMEN1
SCHEMBL5196444 0.89 SLC1A3 (0.55) SLC1A1SLC1A3SLC1A2KMT2AMEN1
SCHEMBL19853461 0.89 SLC1A3 (0.55) SLC1A1SLC1A3SLC1A2KMT2AMEN1
Hydrochloric Acid SCHEMBL19614462 0.88 SLC1A3 (0.54) SLC1A1SLC1A3SLC1A2KMT2AMEN1
Hydrochloric Acid SCHEMBL19614467 0.88 SLC1A3 (0.54) SLC1A1SLC1A3SLC1A2KMT2AMEN1
Hydrochloric Acid SCHEMBL19614463 0.88 SLC1A3 (0.54) SLC1A1SLC1A3SLC1A2KMT2AMEN1
Oxalic Acid SCHEMBL29400639 0.87 SLC1A3 (0.53) SLC1A1SLC1A3SLC1A2KMT2AMEN1
SCHEMBL15289876 0.82 ALDH1A1 (0.53) SLC1A1SLC1A3SLC1A2KMT2AMEN1
SCHEMBL16561116 0.82 ALDH1A1 (0.53) SLC1A1SLC1A3SLC1A2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3041468-B1 CYCLIC PEPTIDOMIMETIC COMPOUNDS AS IMMUNOMODULATORS AURIGENE DISCOVERY TECH LTD (IN) 2018-06-13 EP disclosed
EP-3041828-B1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE DERIVATIVES AS IMMUNOMODULATORS AURIGENE DISCOVERY TECH LTD (IN) 2018-05-23 EP disclosed