Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171125 | 0.81 | — | — | |
| SCHEMBL6469847 | 0.70 | — | — | |
| SCHEMBL8375568 | 0.61 | — | — | |
| SCHEMBL18577008 | 0.58 | OR51E2 (0.35) | — | |
| SCHEMBL18898349 | 0.57 | CRBN (0.40) | GAA | |
| SCHEMBL9721883 | 0.57 | NOS3 (0.38) | — | |
| SCHEMBL20931316 | 0.57 | — | — | |
| SCHEMBL12148566 | 0.57 | — | — | |
| SCHEMBL24697088 | 0.55 | FABP6 (0.37) | ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL3248043 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2772480-B2 | HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2020-12-09 | — | — | EP | disclosed |
| EP-2772480-B1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2018-05-23 | — | — | EP | disclosed |