Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20275179 | 0.90 | POLB (0.36) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL16559840 | 0.90 | POLB (0.40) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL22023580 | 0.89 | POLB (0.37) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL16559836 | 0.88 | POLB (0.40) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL17538614 | 0.87 | POLB (0.43) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL19158978 | 0.86 | FFAR1 (0.40) | POLBAPEX1HTTTDP1FFAR1 | |
| SCHEMBL16573113 | 0.85 | POLB (0.45) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL23350596 | 0.84 | POLB (0.36) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL21675468 | 0.84 | POLB (0.36) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL20275159 | 0.83 | POLB (0.36) | POLBAPEX1HTTTDP1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521401-A1 | COMPOUNDS FOR HOMEOTROPIC ALIGNMENT OF LIQUID CRYSTALINE MEDIA | Merck Patent GmbH (DE) | 2019-08-07 | — | — | EP | disclosed |
| EP-3323872-A1 | COMPOUNDS FOR HOMOTROPIC ALIGNMENT OF LIQUID CRYSTAL MEDIA | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |