Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806035 | 0.88 | ELANE (0.38) | MAPTPOLBAPEX1HTTTDP1 | |
| SCHEMBL26000466 | 0.88 | ACACB (0.31) | — | |
| SCHEMBL21886004 | 0.79 | ELANE (0.38) | MAPTPOLBAPEX1HTTTDP1 | |
| SCHEMBL24173107 | 0.76 | TSHR (0.41) | POLBAPEX1HTTTDP1 | |
| SCHEMBL21231953 | 0.74 | MAPT (0.42) | MAPTTDP1 | |
| SCHEMBL18806020 | 0.74 | ELANE (0.43) | — | |
| SCHEMBL25570168 | 0.74 | ELANE (0.41) | — | |
| SCHEMBL18808067 | 0.74 | ALOX5 (0.33) | TDP1 | |
| SCHEMBL25936844 | 0.73 | ELANE (0.41) | — | |
| SCHEMBL23543260 | 0.72 | FFAR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162875-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |