Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | BCR | P11274 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21231953 | 0.93 | MAPT (0.42) | MAPK1TSHRACACBALDH1A1CYP3A4 | |
| SCHEMBL18806039 | 0.91 | ELANE (0.41) | ABL1ABCB1BCRHPGDLMNA | |
| SCHEMBL25570389 | 0.87 | CYP2C19 (0.38) | ACACBFFAR1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL25570407 | 0.85 | CYP2C19 (0.37) | ERCC5FEN1MAPK1HPGDLMNA | |
| SCHEMBL18806020 | 0.83 | ELANE (0.43) | LMNAACACBSMN1; SMN2KMT2A | |
| SCHEMBL18808061 | 0.82 | FFAR1 (0.35) | CYP3A4FFAR1CYP2C8 | |
| SCHEMBL18808164 | 0.82 | CYP2C19 (0.40) | ABL1CYP3A4SMN1; SMN2KDM4ECYP1A1 | |
| SCHEMBL25638701 | 0.81 | AMY1A (0.36) | MAPK1TSHRALDH1A1FFAR1GLA | |
| SCHEMBL21693395 | 0.81 | ABCB1 (0.38) | ABCB1ERCC5FEN1MAPK1HPGD | |
| SCHEMBL21693412 | 0.81 | FFAR1 (0.46) | MAPK1LMNAFFAR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162875-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |