SCHEMBL20172084

SCHEMBL20172084

Ic1cccc2c1N(c1ccccc1)c1ccncc1O2

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CDK8 P49336 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
THPO P40225 1/20 0.32
FGFR1 P11362 1/20 0.31
MAPK1 P28482 1/20 0.30
CYP17A1 P05093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20308277 0.89 ALDH1A1 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL21415293 0.83 CA12 (0.34) CA12CA1CA2CA9ALDH1A1
SCHEMBL17489712 0.83 CA12 (0.36) CA12CA1CA2CA9ALDH1A1
SCHEMBL20308230 0.74 KDM4E (0.33)
SCHEMBL20308279 0.73 ALDH1A1 (0.38) CA12CA1CA2CA9ALDH1A1
SCHEMBL17490040 0.72 CYP1A2 (0.34) CA12CA1CA2CA9ALDH1A1
SCHEMBL20308081 0.72 ALDH1A1 (0.38) ALDH1A1CDK8FGFR1MAPK1
SCHEMBL17489707 0.72 CDK8 (0.38) CA12CA1CA2CA9ALDH1A1
SCHEMBL20172085 0.71 MAPT (0.36) CA12CA1CA2CA9ALDH1A1
SCHEMBL17490203 0.71 PIM1 (0.37) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3339395-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2018-06-27 EP disclosed
EP-2980182-B1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2018-05-23 EP disclosed