Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TPO | P07202 | 1/20 | 0.46 |
| ▸ | EPX | P11678 | 1/20 | 0.46 |
| ▸ | LPO | P22079 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799461 | 0.84 | MPO (0.44) | MPOTPOEPXLPOSLC6A4 | |
| SCHEMBL159190 | 0.84 | MPO (0.51) | MPOTPOEPXLPOSLC6A4 | |
| SCHEMBL11961092 | 0.83 | ERBB2 (0.49) | KCNH2MAPTL3MBTL1RAB9AKMT2A | |
| SCHEMBL12855074 | 0.82 | ACACB (0.44) | MPOTPOEPXLPOSLC6A4 | |
| SCHEMBL2736376 | 0.82 | MPO (0.42) | MPOTPOEPXLPOMAPT | |
| SCHEMBL12851586 | 0.82 | CYP2C19 (0.46) | MPOTPOEPXLPOL3MBTL1 | |
| SCHEMBL875575 | 0.81 | TTR (0.45) | MPOTPOEPXLPOMAPT | |
| SCHEMBL875619 | 0.81 | TTR (0.46) | MPOTPOEPXLPOMAPT | |
| SCHEMBL11420788 | 0.81 | HTR2A (0.50) | SLC6A4HTR2AKCNH2MAPTL3MBTL1 | |
| SCHEMBL11415800 | 0.80 | SLC6A2 (0.50) | MPOTPOEPXLPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2680850-B1 | ALKYNE SUBSTITUTED QUINAZOLINE COMPOUND AND METHODS OF USE | NEWGEN THERAPEUTICS INC (US) | 2018-05-23 | — | — | EP | disclosed |