Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 19/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26081106 | 1.00 | CTSC (0.47) | CTSCKCNH2SSTR4 | |
| SCHEMBL25046589 | 0.78 | SSTR4 (0.49) | CTSCKCNH2SSTR4 | |
| SCHEMBL24973027 | 0.77 | CTSC (0.54) | CTSCKCNH2 | |
| SCHEMBL6039537 | 0.77 | SSTR4 (0.49) | CTSCSSTR4 | |
| Hydrochloric Acid SCHEMBL29189762 | 0.76 | SSTR4 (0.48) | CTSCKCNH2SSTR4 | |
| SCHEMBL26668539 | 0.76 | SSTR4 (0.48) | CTSCSSTR4 | |
| SCHEMBL24697125 | 0.75 | CTSK (0.43) | — | |
| SCHEMBL24697974 | 0.75 | CTSK (0.43) | — | |
| SCHEMBL8860932 | 0.74 | SSTR4 (0.52) | CTSCSSTR4 | |
| SCHEMBL18664465 | 0.74 | SSTR4 (0.52) | CTSCSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129989-A1 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | Haisco Pharmaceuticals Pte. Ltd. (SG) | 2023-02-08 | — | — | EP | disclosed |
| EP-3323814-B1 | (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE I INHIBITORS | ASTRAZENECA AB (SE) | 2020-05-13 | — | — | EP | disclosed |
| EP-3323814-A1 | (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE I INHIBITORS | AstraZeneca AB (SE) | 2018-05-23 | — | — | EP | disclosed |