Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.58 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CD74 | P04233 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16948382 | 0.83 | MIF (0.58) | MIFMAPTCD74KMT2AMEN1 | |
| SCHEMBL8180452 | 0.82 | MIF (0.63) | MIFIDO1MAPTCD74KMT2A | |
| SCHEMBL30538007 | 0.82 | CBX7 (0.50) | MIFIDO1CD74KMT2AKMO | |
| SCHEMBL16932308 | 0.82 | CBX7 (0.50) | MIFIDO1CD74KMT2AKMO | |
| SCHEMBL16939089 | 0.82 | KMO (0.52) | MIFIDO1CD74KMT2AKMO | |
| SCHEMBL25462884 | 0.80 | IDO1 (0.45) | MIFIDO1MAPTCD74KMT2A | |
| SCHEMBL30387356 | 0.78 | MAPK1 (0.62) | MIFIDO1MAPT | |
| SCHEMBL21992180 | 0.76 | MIF (0.56) | MIFIDO1CD74KMT2A | |
| SCHEMBL8218368 | 0.74 | MIF (0.53) | MIFIDO1MAPTCD74KMT2A | |
| SCHEMBL18805703 | 0.74 | MIF (1.00) | MIFIDO1MAPTCD74KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323814-A1 | (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE I INHIBITORS | AstraZeneca AB (SE) | 2018-05-23 | — | — | EP | disclosed |