Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20173665 | 1.00 | CYP3A4 (0.49) | CYP3A4TSHRATMTDP1MGLL | |
| SCHEMBL11287718 | 1.00 | CYP3A4 (0.49) | CYP3A4TSHRATMTDP1MGLL | |
| SCHEMBL11287723 | 0.95 | MGLL (0.47) | CYP3A4TSHRATMTDP1MGLL | |
| SCHEMBL28545053 | 0.85 | MGLL (0.50) | MGLLALDH1A1LMNAPOLBLPAR1 | |
| SCHEMBL11288097 | 0.85 | MGLL (0.50) | MGLLALDH1A1LMNAPOLBLPAR1 | |
| SCHEMBL28543835 | 0.85 | MGLL (0.50) | MGLLALDH1A1LMNAPOLBLPAR1 | |
| SCHEMBL29617429 | 0.85 | MGLL (0.50) | MGLLALDH1A1LMNAPOLBLPAR1 | |
| SCHEMBL15397388 | 0.84 | LPAR1 (0.52) | MGLLLPAR1LPAR3 | |
| SCHEMBL29316648 | 0.84 | MGLL (0.45) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL471890 | 0.84 | MGLL (0.60) | CYP3A4MGLLALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180142137-A1 | AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE SOLID COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME | THE LUBRIZOL CORPORATION | 2018-05-24 | — | — | US | disclosed |