Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 6/20 | 0.63 |
| ▸ | APP | P05067 | 3/20 | 0.56 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12530962 | 0.88 | APP (0.61) | IDH2APPKCNH3LMNAMAPT | |
| SCHEMBL20174132 | 0.84 | GAA (0.54) | IDH2KCNH3LMNAMAPTMAPK1 | |
| SCHEMBL4544825 | 0.83 | APP (0.65) | IDH2APPKCNH3LMNAMAPT | |
| SCHEMBL10119658 | 0.82 | IDH2 (0.50) | IDH2KCNH3LMNAAURKA | |
| SCHEMBL30568833 | 0.78 | IDH2 (1.00) | IDH2APPLMNAMAPTMAPK1 | |
| SCHEMBL16312221 | 0.77 | GAA (0.61) | IDH2KCNH3LMNAMAPTMAPK1 | |
| SCHEMBL28455381 | 0.77 | IDH2 (0.91) | IDH2APPLMNAMAPTMAPK1 | |
| SCHEMBL6033627 | 0.76 | APP (0.59) | APPKCNH3LMNAMAPTMAPK1 | |
| SCHEMBL4569978 | 0.74 | LMNA (0.71) | IDH2KCNH3LMNAMAPTMAPK1 | |
| SCHEMBL13771505 | 0.74 | APP (0.76) | IDH2APPLMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180142064-A1 | TRIAZINE RING-CONTAINING POLYMER, AND COMPOSITION FOR FILM FORMATION USE CONTAINING SAME | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-05-24 | — | — | US | disclosed |