SCHEMBL20174153

SCHEMBL20174153

C=C(C)C(=O)Oc1ccc(C#Cc2ccc(OC(=O)C(=C)C)c(OC(=O)C(=C)C)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.48
KMT2A Q03164 3/20 0.44
ATM Q13315 1/20 0.44
ACACB O00763 8/20 0.39
FFAR1 O14842 3/20 0.37
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
RAB9A P51151 2/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
APP P05067 1/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NFKB1 P19838 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16541891 0.94 ACACB (0.42) ELANEKMT2AATMACACBFFAR1
SCHEMBL15338893 0.92 ACACB (0.40) ELANEKMT2AATMACACBKDM4E
SCHEMBL16541900 0.90 ELANE (0.44) ELANEKMT2AATMACACBFFAR1
SCHEMBL20174164 0.90 ELANE (0.44) ELANEKMT2AATMACACBFFAR1
SCHEMBL15339104 0.90 ELANE (0.40) ELANEKMT2AATMACACBFFAR1
SCHEMBL16182736 0.89 ELANE (0.57) ELANEKMT2AATMACACBFFAR1
SCHEMBL7766154 0.89 ELANE (0.57) ELANEKMT2AATMACACBFFAR1
SCHEMBL16182693 0.89 ELANE (0.57) ELANEKMT2AATMACACBFFAR1
SCHEMBL17370251 0.88 ELANE (0.46) ELANEKMT2AATMACACBFFAR1
SCHEMBL17370475 0.88 ELANE (0.46) ELANEKMT2AATMACACBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200301213-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2020-09-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed