SCHEMBL20174164

SCHEMBL20174164

C=C(C)C(=O)Oc1ccc(C#Cc2ccc(-c3ccc(OC(=O)C(=C)C)c(OC(=O)C(=C)C)c3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.44
KMT2A Q03164 4/20 0.42
ATM Q13315 1/20 0.42
GAA P10253 2/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 2/20 0.36
CFD P00746 1/20 0.35
MAPT P10636 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
GAPDH P04406 1/20 0.34
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
BACE1 P56817 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
THRB P10828 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16541900 1.00 ELANE (0.44) ELANEKMT2AATMGAALMNA
SCHEMBL19186969 0.94 CFD (0.38) ELANEKMT2AATMGAALMNA
SCHEMBL16541894 0.92 ACACB (0.38) ELANEKMT2AATMGAAHSD17B10
SCHEMBL16541920 0.92 ACACB (0.38) ELANEKMT2AATMGAAHSD17B10
SCHEMBL16803381 0.91 ELANE (0.51) ELANEKMT2AATMGAALMNA
SCHEMBL15625536 0.91 ELANE (0.51) ELANEKMT2AATMGAALMNA
SCHEMBL20174153 0.90 ELANE (0.48) ELANEKMT2AATMGAATDP1
SCHEMBL17370637 0.89 ELANE (0.43) ELANEKMT2AATMGAALMNA
SCHEMBL17370693 0.89 ELANE (0.43) ELANEKMT2AATMGAALMNA
SCHEMBL17370514 0.88 ELANE (0.47) ELANEKMT2AATMGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200301213-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2020-09-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed