SCHEMBL20174162

SCHEMBL20174162

C=C(C)C(=O)OCCCOc1ccc(OC(=O)c2ccc(-c3ccc(OCCOC(=O)C(=C)C)cc3)cc2F)cc1OCCCOC(=O)C(=C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.46
RARA P10276 2/20 0.46
POLB P06746 2/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
PPARD Q03181 3/20 0.34
PPARG P37231 2/20 0.34
PPARA Q07869 2/20 0.34
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
NFKB1 P19838 1/20 0.33
BLM P54132 1/20 0.33
RARG P13631 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20174172 0.85 POLB (0.47) RARBRARAPOLBAPEX1HTT
SCHEMBL16982209 0.82 POLB (0.48) RARBRARAPOLBAPEX1HTT
SCHEMBL17072093 0.82 POLB (0.45) RARBRARAPOLBAPEX1HTT
SCHEMBL13829066 0.81 POLB (0.50) RARBRARAPOLBAPEX1HTT
SCHEMBL24440947 0.81 POLB (0.47) RARBRARAPOLBAPEX1HTT
SCHEMBL22754586 0.81 RARB (0.40) RARBRARAPOLBAPEX1HTT
SCHEMBL13828984 0.80 POLB (0.45) RARBRARAPOLBAPEX1HTT
SCHEMBL19804557 0.80 MAPT (0.40) RARBRARAPOLBAPEX1HTT
SCHEMBL13829015 0.80 POLB (0.54) POLBAPEX1HTTTDP1KMT2A
SCHEMBL16559821 0.79 POLB (0.41) RARBRARAPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200301213-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2020-09-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed