SCHEMBL20174172

SCHEMBL20174172

C=C(C)C(=O)OCCCOc1ccc(C(=O)Oc2ccc(-c3ccc(OCCOC(=O)C(=C)C)cc3)cc2F)cc1OCCCOC(=O)C(=C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
RARB P10826 2/20 0.39
RARA P10276 1/20 0.39
CASP6 P55212 1/20 0.38
KMT2A Q03164 4/20 0.37
FAAH O00519 2/20 0.37
NPC1 O15118 1/20 0.37
S1PR1 P21453 1/20 0.36
MAPT P10636 2/20 0.35
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34
MEN1 O00255 2/20 0.34
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13289817 0.87 POLB (0.53) POLBAPEX1HTTTDP1RARB
SCHEMBL13289815 0.87 POLB (0.55) POLBAPEX1HTTTDP1RARB
SCHEMBL24440947 0.86 POLB (0.47) POLBAPEX1HTTTDP1RARB
SCHEMBL20174162 0.85 RARB (0.46) POLBAPEX1HTTTDP1RARB
SCHEMBL16982209 0.85 POLB (0.48) POLBAPEX1HTTTDP1RARB
SCHEMBL13837965 0.84 POLB (0.55) POLBAPEX1HTTTDP1KMT2A
SCHEMBL11961775 0.84 TDP1 (0.49) POLBAPEX1HTTTDP1CASP6
SCHEMBL16559821 0.84 POLB (0.41) POLBAPEX1HTTTDP1RARB
SCHEMBL16559841 0.84 THRB (0.39) POLBAPEX1HTTTDP1RARB
SCHEMBL17072093 0.83 POLB (0.45) POLBAPEX1HTTTDP1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200301213-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2020-09-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed