Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | ESR1 | P03372 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.65 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | STS | P08842 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918679 | 1.00 | NPC1 (0.73) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL10332514 | 1.00 | NPC1 (0.73) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL1937111 | 1.00 | NPC1 (0.73) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL13763479 | 1.00 | NPC1 (0.73) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL13227995 | 0.98 | NPC1 (0.71) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL13412591 | 0.98 | NPC1 (0.71) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL17565215 | 0.97 | NPC1 (0.69) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL16706151 | 0.95 | NPC1 (0.68) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL19649668 | 0.95 | LMNA (0.72) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL6057132 | 0.93 | TSHR (0.74) | NPC1RAB9AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180143548-A1 | COLD PRESSURE FIX TONER COMPOSITIONS BASED ON SMALL MOLECULE CRYSTALLINE AND AMORPHOUS ORGANIC COMPOUND MIXTURES | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2018-05-24 | — | — | US | disclosed |