Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800825 | 1.00 | HPGD (0.52) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL9172953 | 0.93 | HPGD (0.54) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL28779594 | 0.90 | HPGD (0.50) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL2775710 | 0.89 | HPGD (0.53) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL10575936 | 0.86 | HPGD (0.53) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL10573662 | 0.86 | HPGD (0.53) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL10573657 | 0.86 | HPGD (0.53) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL21647341 | 0.86 | HPGD (0.50) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL9447785 | 0.85 | HPGD (0.57) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL19901306 | 0.85 | HPGD (0.47) | HPGDLMNAALDH1A1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2856218-B9 | FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | BAUSCH & LOMB (US) | 2016-11-30 | — | — | EP | claimed |
| EP-2856218-B1 | FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | BAUSCH & LOMB (US) | 2016-07-27 | — | — | EP | claimed |
| EP-2856219-B1 | METHOD OF MAKING A FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | BAUSCH & LOMB (US) | 2016-04-13 | — | — | EP | claimed |
| US-9075187-B2 | Fully polymerized UV blocking silicone hydrogel lens | BAUSCH & LOMB INCORPORATED (US) | 2015-07-07 | — | — | US | claimed |
| US-8807745-B2 | Fully polymerized UV blocking silicone hydrogel lens | BAUSCH & LOMB INCORPORATED (US) | 2014-08-19 | — | — | US | claimed |
| US-20130313733-A1 | METHOD OF MAKING A FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | MEDICIS PHARMACEUTICAL CORPORATION | 2013-11-28 | — | — | US | claimed |
| EP-3004050-B1 | CYANOSTILBENES | ROLIC TECH AG (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
| EP-2856218-B9 | FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | BAUSCH & LOMB (US) | 2016-11-30 | — | — | EP | disclosed |
| EP-2856218-B1 | FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | BAUSCH & LOMB (US) | 2016-07-27 | — | — | EP | disclosed |
| EP-2373710-B1 | MICROSTRUCTURED OPTICAL FILMS COMPRISING POLYMERIZABLE ULTRAVIOLET ABSORBER | 3M INNOVATIVE PROPERTIES CO (US) | 2016-04-13 | — | — | EP | disclosed |
| EP-2856219-B1 | METHOD OF MAKING A FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | BAUSCH & LOMB (US) | 2016-04-13 | — | — | EP | disclosed |
| US-20160097884-A1 | MICROSTRUCTURED OPTICAL FILMS COMPRISING FLUORENE-CONTAINING MONOMER | 3M INNOVATIVE PROPERTIES CO (US) | 2016-04-07 | — | — | US | disclosed |
| US-5700576-A | ACRYLATED ESTER POLYMERS | ROEHM GMBH CHEMISCHE FABRIK (DE) | 1997-12-23 | — | — | US | disclosed |
| EP-0802219-A2 | Coated aliphatic polyester film | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-10-22 | — | — | EP | disclosed |
| US-5663288-A | Degradable adhesive film and degradable resin composition | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5489474-A | LACTIC ACID BASE POLYMER | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0677561-A1 | Degradable resin composition | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |
| EP-0587069-A1 | Degradable adhesive film and degradable resin composition | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4824892-A | UV light stabilizer based on benzophenone | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1989-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329486-B2 | Cyanostilbenes | LATS1, LATS2, CRY1 | HPGD 4309/4885LMNA 166/4885ALDH1A1 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.