SCHEMBL2017576

SCHEMBL2017576

N[C@@H](COP(=O)(O)OC[C@@H](O)CO)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 16/20 0.56
GPR174 Q9BXC1 10/20 0.56
GPR34 Q9UPC5 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30244695 1.00 P2RY10 (0.56) P2RY10GPR174GPR34
SCHEMBL29715574 1.00 P2RY10 (0.56) P2RY10GPR174GPR34
SCHEMBL22219423 1.00 P2RY10 (0.56) P2RY10GPR174GPR34
SCHEMBL21067706 1.00 P2RY10 (0.56) P2RY10GPR174GPR34
SCHEMBL13863415 1.00 P2RY10 (0.56) P2RY10GPR174GPR34
Dexfosfoserine SCHEMBL28051238 0.84 PGK1 (0.53) P2RY10GPR174GPR34
SCHEMBL30244795 0.83 P2RY10 (0.41) P2RY10GPR174GPR34
SCHEMBL29556656 0.83 P2RY10 (0.41) P2RY10GPR174GPR34
SCHEMBL13618513 0.83 P2RY10 (0.60) P2RY10GPR174GPR34
SCHEMBL12284729 0.83 SMN1; SMN2 (0.46) P2RY10GPR174GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118265522-A Lipid-based RNA formulations suitable for treatment 生物技术欧洲股份公司 2024-06-28 CN claimed
US-20030026831-A1 Anionic liposomes for delivery of bioactive agents REGENTS OF THE UNIVERSITY OF MINNESOTA 2003-02-06 US claimed
EP-3548002-B1 HYDROPHILIC FLUORINATED MOLECULES FOR LIPOSOMAL 19F MRI PROBES WITH UNIQUE MR SIGNATURES Texas Childrens Hospital (US) 2025-04-30 EP disclosed
CN-118265522-A Lipid-based RNA formulations suitable for treatment 生物技术欧洲股份公司 2024-06-28 CN disclosed
WO-2024107474-A1 CONTROLLED LIPID SELF-ASSEMBLY FOR SCALABLE MANUFACTURING OF NEXT-GENERATION IMMUNE STIMULATING COMPLEXES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-05-23 WO disclosed
US-20240165029-A1 ASSISTED LOADING OF HYDROPHOBIC MOLECULES INTO LIPOSOMES UNIVERSITY OF CONNECTICUT 2024-05-23 US disclosed
WO-2024035783-A2 SULFUR-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF FOR DELIVERY OF NUCLEIC ACIDS POSEIDA THERAPEUTICS, INC. (US) 2024-02-15 WO disclosed
WO-2023180183-A1 LIPOSOMAL COMPOSITIONS R.G.C.C. Holdings AG (CH) 2023-09-28 WO disclosed
EP-4248949-A1 LIPOSOMAL COMPOSITIONS R.G.C.C. Holdings AG (CH) 2023-09-27 EP disclosed
US-20230158507-A1 BIOLOGICAL MEMBRANE-BASED SENSOR MCMASTER UNIVERSITY (CA) 2023-05-25 US disclosed
CN-115350154-A Lipid cake for preparing anesthetic composition and use thereof 美商TLC生物医药公司 2022-11-18 CN disclosed
WO-2006002050-A1 PHOSPHOLIPID COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE ENCORE THERAPEUTICS, INC. (US) 2006-01-05 WO disclosed
WO-2005016308-A1 MACROLIDES CONTAINING OIL-IN-WATER EMULSIONS SD PHARMACEUTICALS, INC. (US) 2005-02-24 WO disclosed
US-20030026831-A1 Anionic liposomes for delivery of bioactive agents REGENTS OF THE UNIVERSITY OF MINNESOTA 2003-02-06 US disclosed
EP-0943096-A4 A PROTEIN PREPARATION THAT MEDIATES Ca2+ -DEPENDENT TRANSBILAYER MOVEMENT OF PLASMA MEMBRANE PHOSPHOLIPID AND INHIBITORS THEREOF BLOOD CT RES FOUNDATION (US) 2001-02-07 EP disclosed
EP-1030866-A2 METHODS AND COMPOSITIONS TO ALTER THE CELL SURFACE EXPRESSION OF PHOSPHATIDYLSERINE AND OTHER CLOT-PROMOTING PLASMA MEMBRANE PHOSPHOLIPIDS BLOOD CENTER RESEARCH FOUNDATION (US) 2000-08-30 EP disclosed
EP-0943096-A1 A PROTEIN PREPARATION THAT MEDIATES Ca2+ -DEPENDENT TRANSBILAYER MOVEMENT OF PLASMA MEMBRANE PHOSPHOLIPID AND INHIBITORS THEREOF BLOOD CENTER RESEARCH FOUNDATION (US) 1999-09-22 EP disclosed
WO-1999019352-A2 METHODS AND COMPOSITIONS TO ALTER THE CELL SURFACE EXPRESSION OF PHOSPHATIDYLSERINE AND OTHER CLOT-PROMOTING PLASMA MEMBRANE PHOSPHOLIPIDS BLOOD CENTER RESEARCH FOUNDATION (US) 1999-04-22 WO disclosed
WO-1997037225-A1 A PROTEIN PREPARATION THAT MEDIATES Ca2+-DEPENDENT TRANSBILAYER MOVEMENT OF PLASMA MEMBRANE PHOSPHOLIPID AND INHIBITORS THEREOF BLOOD CENTER RESEARCH FOUNDATION (US) 1997-10-09 WO disclosed
EP-0181465-A1 Blood coagulation inhibiting proteins, process for preparing them and their use BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 1986-05-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240165029-A1 ASSISTED LOADING OF HYDROPHOBIC MOLECULES INTO LIPOSOMES LIPA, MICA, TLR9 P2RY10 2925/4885GPR174 3846/4885GPR34 3126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.