Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24113775 | 0.91 | SPHK2 (0.39) | SPHK2SPHK1 | |
| SCHEMBL5077263 | 0.91 | SPHK2 (0.39) | SPHK2SPHK1 | |
| SCHEMBL1276923 | 0.87 | SPHK2 (0.31) | SPHK2SPHK1 | |
| SCHEMBL13864565 | 0.87 | SPHK2 (0.31) | SPHK2SPHK1 | |
| SCHEMBL17219655 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL24113758 | 0.85 | SPHK2 (0.41) | SPHK2SPHK1 | |
| SCHEMBL11276646 | 0.83 | TSHR (0.32) | — | |
| SCHEMBL21161 | 0.82 | ALDH1A1 (0.38) | — | |
| SCHEMBL6556705 | 0.82 | ALDH1A1 (0.30) | — | |
| SCHEMBL251421 | 0.82 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-06-27 | — | — | US | disclosed |
| US-20180142152-A1 | COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | LPXN, VCL, LCP1 | SPHK2 1848/4885SPHK1 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.