Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27144759 | 0.87 | MCHR1 (0.52) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL27138957 | 0.87 | ALDH1A1 (0.58) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL31413480 | 0.87 | ALDH1A1 (0.58) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL12302240 | 0.86 | ALDH1A1 (0.56) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL1285834 | 0.86 | SIRT2 (0.55) | KDM4ENPC1RAB9ANPSR1TP53 | |
| SCHEMBL1643366 | 0.85 | TP53 (0.61) | TP53HRH3HDAC3HDAC2ALDH1A1 | |
| SCHEMBL10271626 | 0.85 | SIRT2 (0.53) | KDM4ENPC1RAB9ATP53HRH3 | |
| SCHEMBL12331989 | 0.84 | HRH3 (0.53) | KDM4ENPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL1643347 | 0.83 | TP53 (0.60) | TP53HRH3HDAC3HDAC2ALDH1A1 | |
| SCHEMBL1644303 | 0.83 | HRH3 (0.53) | KDM4ENPSR1TP53HRH3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141923-A1 | SELECTIVE HDAC1,2 INHIBITORS | REGENACY PHARMACEUTICALS, LLC | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141923-A1 | SELECTIVE HDAC1,2 INHIBITORS | HDAC1, HDAC2, HDAC11 | KDM4E 514/4885NPC1 512/4885RAB9A 2395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.