Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404868 | 0.83 | PIK3CD (0.72) | ALDH1A1PIK3CDPIK3CAPIK3CBMAPT | |
| SCHEMBL8738721 | 0.81 | PIK3CD (0.56) | ALDH1A1PIK3CDPIK3CAPIK3CBMAPT | |
| SCHEMBL13787617 | 0.81 | PIK3CD (0.74) | ALDH1A1PIK3CDPIK3CAPIK3CBMAPT | |
| Hydrochloric Acid SCHEMBL6113991 | 0.80 | PIK3CD (0.55) | ALDH1A1PIK3CDPIK3CAPIK3CBMAPT | |
| SCHEMBL21875361 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL17452584 | 0.77 | PIK3CD (0.52) | ALDH1A1PIK3CDPIK3CAPIK3CBMAPT | |
| SCHEMBL20229568 | 0.77 | PIK3CD (0.52) | ALDH1A1PIK3CDPIK3CAPIK3CBMAPT | |
| SCHEMBL13329792 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL8738724 | 0.76 | PIK3CD (0.51) | ALDH1A1PIK3CDPIK3CAPIK3CBMAPT | |
| Bromide SCHEMBL6113981 | 0.75 | PIK3CD (0.50) | ALDH1A1PIK3CDPIK3CAPIK3CBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141923-A1 | SELECTIVE HDAC1,2 INHIBITORS | REGENACY PHARMACEUTICALS, LLC | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141923-A1 | SELECTIVE HDAC1,2 INHIBITORS | HDAC1, HDAC2, HDAC11 | ALDH1A1 1155/4885PIK3CD 2084/4885PIK3CA 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.